Which is faster an slot or PCI-E slots for an drive?

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In this video I discuss the difference between an SSD and a NVME PCI-Ex4 SSD From how

What is the difference between SSD vs mSATA SSD? · MSATA SSDs only use the SATA interface, while SSDs support SATA or PCIe interfaces · The newer M · An For example, a drive that is 22mm wide and 80mm long would be listed as being a 2280 Common lengths for drives and mounting

king78 slot 2 slots are M-key, but some are B+M-key, and some are E-key  For example, a drive that is 22mm wide and 80mm long would be listed as being a 2280 Common lengths for drives and mounting